Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization

BACKGROUND: Psoriasis impacts 1–3% of the world’s population and is characterized by hyper-proliferation of keratinocytes and increased inflammation. At the molecular level, psoriasis is commonly driven by a Th17 response, which serves as a major therapeutic target. Microbiome perturbations have bee...

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Veröffentlicht in:Microbiome
Hauptverfasser: Chang, Hsin-Wen, Yan, Di, Singh, Rasnik, Liu, Jared, Lu, Xueyan, Ucmak, Derya, Lee, Kristina, Afifi, Ladan, Fadrosh, Douglas, Leech, John, Vasquez, Kimberly S., Lowe, Margaret M., Rosenblum, Michael D., Scharschmidt, Tiffany C., Lynch, Susan V., Liao, Wilson
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125946/
https://ncbi.nlm.nih.gov/pubmed/30185226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-018-0533-1
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