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Step-Wise Epigenetic and Phenotypic Alterations Poise CD8(+) T Cells to Mediate Airway Hyperresponsiveness and Inflammation
The functional plasticity of CD8(+) T cells in an atopic environment, encompassing a spectrum from IFN-γ- to IL-13-producing cells, is pivotal in the development of allergic airway hyperresponsiveness (AHR) and inflammation and yet remains mechanistically undefined. We demonstrate that CD8(+) T cell...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622148/ https://ncbi.nlm.nih.gov/pubmed/23509358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202640 |
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