Aire-dependent thymic development of tumor-associated regulatory T cells

Despite considerable interest in the modulation of tumor-associated Foxp3(+) regulatory T cells (Tregs) for therapeutic benefit, little is known about the developmental origins of these cells and the nature of the antigens that they recognize. Here, we identified an endogenous population of antigen-...

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Autori principali: Malchow, Sven, Leventhal, Daniel S., Nishi, Saki, Fischer, Benjamin I., Shen, Lynn, Paner, Gladell P., Amit, Ayelet S., Kang, Chulho, Geddes, Jenna E., Allison, James P., Socci, Nicholas D., Savage, Peter A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622085/
https://ncbi.nlm.nih.gov/pubmed/23471412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1233913
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