Aire-dependent thymic development of tumor-associated regulatory T cells

Despite considerable interest in the modulation of tumor-associated Foxp3(+) regulatory T cells (Tregs) for therapeutic benefit, little is known about the developmental origins of these cells and the nature of the antigens that they recognize. Here, we identified an endogenous population of antigen-...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Malchow, Sven, Leventhal, Daniel S., Nishi, Saki, Fischer, Benjamin I., Shen, Lynn, Paner, Gladell P., Amit, Ayelet S., Kang, Chulho, Geddes, Jenna E., Allison, James P., Socci, Nicholas D., Savage, Peter A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622085/
https://ncbi.nlm.nih.gov/pubmed/23471412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1233913
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