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Aire-dependent thymic development of tumor-associated regulatory T cells

Despite considerable interest in the modulation of tumor-associated Foxp3(+) regulatory T cells (Tregs) for therapeutic benefit, little is known about the developmental origins of these cells and the nature of the antigens that they recognize. Here, we identified an endogenous population of antigen-...

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Detalhes bibliográficos
Main Authors: Malchow, Sven, Leventhal, Daniel S., Nishi, Saki, Fischer, Benjamin I., Shen, Lynn, Paner, Gladell P., Amit, Ayelet S., Kang, Chulho, Geddes, Jenna E., Allison, James P., Socci, Nicholas D., Savage, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622085/
https://ncbi.nlm.nih.gov/pubmed/23471412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1233913
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