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Structural Insights into Omega-Class Glutathione Transferases: A Snapshot of Enzyme Reduction and Identification of a Non-Catalytic Ligandin Site

Glutathione transferases (GSTs) are dimeric enzymes containing one active-site per monomer. The omega-class GSTs (hGSTO1-1 and hGSTO2-2 in humans) are homodimeric and carry out a range of reactions including the glutathione-dependant reduction of a range of compounds and the reduction of S-(phenacyl...

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Bibliografiske detaljer
Main Authors: Brock, Joseph, Board, Philip G., Oakley, Aaron J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621891/
https://ncbi.nlm.nih.gov/pubmed/23593192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060324
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