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A New Approach to Establish a Cell Line with Reduced Risk of Endogenous Retroviruses

Endogenous retroviruses (ERVs) are integrated as DNA proviruses in the genomes of all mammalian species. Several ERVs are replication-competent and produced as fully infectious viruses from host cell. Thus, live-attenuated vaccines and biological substances have been prepared using the cell lines wh...

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Detalhes bibliográficos
Main Authors: Fukuma, Aiko, Yoshikawa, Rokusuke, Miyazawa, Takayuki, Yasuda, Jiro
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621756/
https://ncbi.nlm.nih.gov/pubmed/23585909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061530
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