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Establishment of CRFK cells for vaccine production by inactivating endogenous retrovirus with TALEN technology
Abstract Endogenous retroviruses (ERVs) are retroviral sequences present in the host genomes. Although most ERVs are inactivated, some are produced as replication-competent viruses from host cells. We previously reported that several live-attenuated vaccines for companion animals prepared using the...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Portfolio
2022-04-01
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Colecção: | Scientific Reports |
Acesso em linha: | https://doi.org/10.1038/s41598-022-10497-1 |
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