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Establishment of CRFK cells for vaccine production by inactivating endogenous retrovirus with TALEN technology

Abstract Endogenous retroviruses (ERVs) are retroviral sequences present in the host genomes. Although most ERVs are inactivated, some are produced as replication-competent viruses from host cells. We previously reported that several live-attenuated vaccines for companion animals prepared using the...

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Detalhes bibliográficos
Main Authors: Sayumi Shimode, Tetsushi Sakuma, Takashi Yamamoto, Takayuki Miyazawa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2022-04-01
Colecção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-022-10497-1
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