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Modulation of the anti-cancer efficacy of microtubule-targeting agents by cellular growth conditions

Mitotic spindle-disrupting agents target and alter microtubule dynamics. These agents include clinically important chemotherapies, such as taxanes (paclitaxel [Taxol], docetaxel [Taxotere]) and vinca alkaloids (vincristine [Oncovin], vinblastine). Taxanes are a standard component of treatment for ma...

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Main Authors: Dorsey, Jay F., Dowling, Melissa L., Kim, Mijin, Voong, Ranh, Solin, Lawrence J., Kao, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621729/
https://ncbi.nlm.nih.gov/pubmed/20234172
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