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BATF regulates the development and function of IL-17 producing iNKT cells

BACKGROUND: BATF plays important roles in the function of the immune system. Batf null mice are deficient in both CD4(+) Th17 cells and T follicular helper cells and possess an intrinsic B cell defect that leads to the complete absence of class switched Ig. In this study, Tg mice overexpressing BATF...

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Detalhes bibliográficos
Main Authors: Jordan-Williams, Kimberly L, Poston, Stacie, Taparowsky, Elizabeth J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621619/
https://ncbi.nlm.nih.gov/pubmed/23537103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-14-16
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