Secreted Protein Acidic and Rich in Cysteine (SPARC)-Null Mice Exhibit More Uniform Outflow

PURPOSE. Secreted protein acidic and rich in cysteine (SPARC) is a matricellular protein known to regulate extracellular matrix (ECM) in many tissues and is highly expressed in trabecular meshwork (TM). SPARC-null mice have a 15% to 20% decrease in intraocular pressure (IOP) compared to wild-type (W...

Full description

Saved in:
Bibliographic Details
Main Authors: Swaminathan, Swarup S., Oh, Dong-Jin, Kang, Min Hyung, Ren, Ruiyi, Jin, Rui, Gong, Haiyan, Rhee, Douglas J.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2013
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621502/
https://ncbi.nlm.nih.gov/pubmed/23422826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-10950
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items