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Anti-VEGF Antibody Leads to Later Atypical Intravitreous Neovascularization and Activation of Angiogenic Pathways in a Rat Model of Retinopathy of Prematurity

PURPOSE. Inhibiting VEGF improves adult retino/choroido-vascular diseases, but can lead to recurrent intravitreous neovascularization (IVNV), avascular retina (AVA), and retinal detachment in preterm infants with retinopathy of prematurity (ROP). We sought to understand causes of late-onset IVNV and...

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Detalhes bibliográficos
Main Authors: McCloskey, Manabu, Wang, Haibo, Jiang, Yanchao, Smith, George Wesley, Strange, Jeremy, Hartnett, M. Elizabeth
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621501/
https://ncbi.nlm.nih.gov/pubmed/23449716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-11625
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