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Retroviral transduction of the human c-Ha-ras-1 oncogene into midgestation mouse embryos promotes rapid epithelial hyperplasia.

Infection of mouse embryos at 8 days of gestation with a replication-defective retrovirus carrying the human c-Ha-ras-1 oncogene led to efficient and rapid induction of hyperplastic lesions. Twenty-four percent of viable off-spring developed abnormal growths after infection with purified virus. The...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell Biol
Prif Awduron: Compere, S J, Baldacci, P A, Sharpe, A H, Jaenisch, R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 1989
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362139/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2648134/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.1.6-14.1989
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