Retroviral transduction of the human c-Ha-ras-1 oncogene into midgestation mouse embryos promotes rapid epithelial hyperplasia.

Infection of mouse embryos at 8 days of gestation with a replication-defective retrovirus carrying the human c-Ha-ras-1 oncogene led to efficient and rapid induction of hyperplastic lesions. Twenty-four percent of viable off-spring developed abnormal growths after infection with purified virus. The...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Compere, S J, Baldacci, P A, Sharpe, A H, Jaenisch, R
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1989
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC362139/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2648134/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.9.1.6-14.1989
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