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Increased Nuclear Thioredoxin-1 Potentiates Cadmium-Induced Cytotoxicity

Cadmium (Cd) is a widely dispersed environmental agent that causes oxidative toxicity through mechanisms that are sensitive to thioredoxin-1 (Trx1). Trx1 is a cytoplasmic protein that translocates to nuclei during oxidative stress. Recent research shows that interaction of Trx1 with actin plays a cr...

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Detalhes bibliográficos
Main Authors: Go, Young-Mi, Orr, Michael, Jones, Dean P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621352/
https://ncbi.nlm.nih.gov/pubmed/22961094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs271
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