Increased Inflammatory Signaling and Lethality of Influenza H1N1 by Nuclear Thioredoxin-1

BACKGROUND: Cell culture studies show that the antioxidant thiol protein, thioredoxin-1 (Trx1), translocates to cell nuclei during stress, facilitates DNA binding of transcription factors NF-κB and glucocorticoid receptor (GR) and potentiates signaling in immune cells. Excessive proinflammatory sign...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Go, Young-Mi, Kang, Sang-Moo, Roede, James R., Orr, Michael, Jones, Dean P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078150/
https://ncbi.nlm.nih.gov/pubmed/21526215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018918
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