Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy

Whether and how T cells contribute to the pathogenesis of immunoglobulin A nephropathy (IgAN) has not been well defined. Here, we explore a murine model that spontaneously develops T cell–mediated intestinal inflammation accompanied by pathological features similar to those of human IgAN. Intestinal...

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Bibliografiske detaljer
Main Authors: Wang, Jing, Anders, Robert A., Wu, Qiang, Peng, Dacheng, Cho, Judy H., Sun, Yonglian, Karaliukas, Reda, Kang, Hyung-Sik, Turner, Jerrold R., Fu, Yang-Xin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC362120/
https://ncbi.nlm.nih.gov/pubmed/15067315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420096
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