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Dysregulated LIGHT expression on T cells mediates intestinal inflammation and contributes to IgA nephropathy
Whether and how T cells contribute to the pathogenesis of immunoglobulin A nephropathy (IgAN) has not been well defined. Here, we explore a murine model that spontaneously develops T cell–mediated intestinal inflammation accompanied by pathological features similar to those of human IgAN. Intestinal...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC362120/ https://ncbi.nlm.nih.gov/pubmed/15067315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420096 |
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