Significant Increase in Salivary Substance P Level after a Single Oral Dose of Cevimeline in Humans

Cevimeline is a novel muscarinic acetylcholine receptor agonist currently being developed as a therapeutic agent for xerostomia. We examined the effects of cevimeline on salivary and plasma levels of substance-P- (SP-), calcitonin-gene-related-peptide- (CGRP-), and vasoactive-intestinal-polypeptide-...

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Detalhes bibliográficos
Main Authors: Suzuki, Yosuke, Itoh, Hiroki, Amada, Kohei, Yamamura, Ryota, Sato, Yuhki, Takeyama, Masaharu
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621173/
https://ncbi.nlm.nih.gov/pubmed/23589717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/284765
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