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Intra-membrane Signaling Between the Voltage-Gated Ca(2+)-Channel and Cysteine Residues of Syntaxin 1A Coordinates Synchronous Release

The interaction of syntaxin 1A (Sx1A) with voltage-gated calcium channels (VGCC) is required for depolarization-evoked release. However, it is unclear how the signal is transferred from the channel to the exocytotic machinery and whether assembly of Sx1A and the calcium channel is conformationally l...

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Bibliografske podrobnosti
Main Authors: Bachnoff, Niv, Cohen-Kutner, Moshe, Trus, Michael, Atlas, Daphne
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3621091/
https://ncbi.nlm.nih.gov/pubmed/23567899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01620
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