Allele-specific cytokine responses at the HLA-C locus, implications for psoriasis

Psoriasis is an inflammatory skin disorder that is inherited as a complex trait. Genetic studies have repeatedly highlighted HLA-C as the major determinant for psoriasis susceptibility, with the Cw*0602 allele conferring significant disease risk in a wide-range of populations. Despite the potential...

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Detalhes bibliográficos
Main Authors: Hundhausen, Christian, Bertoni, Anna, Mak, Rose K, Botti, Elisabetta, Di Meglio, Paola, Clop, Alex, Laggner, Ute, Chimenti, Sergio, Hayday, Adrian C, Barker, Jonathan N, Trembath, Richard C, Capon, Francesca, Nestle, Frank O
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620929/
https://ncbi.nlm.nih.gov/pubmed/22113476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2011.378
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