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C60-ToF SIMS imaging of frozen hydrated HeLa cells

Sample preparation continues to be a major challenge for secondary ion mass spectrometry studies of biological materials. Maintaining the native hydrated state of the material is important for preserving both chemical and spatial information. Here, we discuss a method which combines a sample wash an...

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Autors principals: Piwowar, Alan M., Keskin, Selda, Delgado, Melissa Ortiz, Shen, Kan, Hue, Jonathan J., Lanekoff, Ingela, Ewing, Andrew G., Winograd, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620711/
https://ncbi.nlm.nih.gov/pubmed/23585702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sia.4882
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