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Minocycline Suppresses Interleukine-6, Its Receptor System and Signaling Pathways and Impairs Migration, Invasion and Adhesion Capacity of Ovarian Cancer Cells: In Vitro and In Vivo Studies

Interleukin (IL)-6 has been shown to be a major contributing factor in growth and progression of ovarian cancer. The cytokine exerts pro-tumorigenic activity through activation of several signaling pathways in particular signal transducer and activator of transcription (STAT3) and extracellular sign...

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Bibliografische gegevens
Hoofdauteurs: Ataie-Kachoie, Parvin, Morris, David L., Pourgholami, Mohammad H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620477/
https://ncbi.nlm.nih.gov/pubmed/23593315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060817
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