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Minocycline Suppresses Interleukine-6, Its Receptor System and Signaling Pathways and Impairs Migration, Invasion and Adhesion Capacity of Ovarian Cancer Cells: In Vitro and In Vivo Studies
Interleukin (IL)-6 has been shown to be a major contributing factor in growth and progression of ovarian cancer. The cytokine exerts pro-tumorigenic activity through activation of several signaling pathways in particular signal transducer and activator of transcription (STAT3) and extracellular sign...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620477/ https://ncbi.nlm.nih.gov/pubmed/23593315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060817 |
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