Mutual Antagonism between Circadian Protein Period 2 and Hepatitis C Virus Replication in Hepatocytes

BACKGROUND: Hepatitis C virus (HCV) infects approximately 3% of the world population and is the leading cause of liver disease, impacting hepatocyte metabolism, depending on virus genotype. Hepatic metabolic functions show rhythmic fluctuations with 24-h periodicity (circadian), driven by molecular...

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Hoofdauteurs: Benegiamo, Giorgia, Mazzoccoli, Gianluigi, Cappello, Francesco, Rappa, Francesca, Scibetta, Nunzia, Oben, Jude, Greco, Azzura, Williams, Roger, Andriulli, Angelo, Vinciguerra, Manlio, Pazienza, Valerio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620463/
https://ncbi.nlm.nih.gov/pubmed/23593233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060527
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