Development of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity

In this study, the potential for development of an animal model (GPG46) capable of rapidly detecting chemical carcinogenicity and the underlying mechanisms of action were examined in gpt delta rats using a reporter gene assay to detect mutations and a medium-term rat liver bioassay to detect tumor p...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Matsushita, Kohei, Kijima, Aki, Ishii, Yuji, Takasu, Shinji, Jin, Meilan, Kuroda, Ken, Kawaguchi, Hiroaki, Miyoshi, Noriaki, Nohmi, Takehiko, Ogawa, Kumiko, Umemura, Takashi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Japanese Society of Toxicologic Pathology 2013
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620210/
https://ncbi.nlm.nih.gov/pubmed/23723564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.26.19
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