Development of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity

In this study, the potential for development of an animal model (GPG46) capable of rapidly detecting chemical carcinogenicity and the underlying mechanisms of action were examined in gpt delta rats using a reporter gene assay to detect mutations and a medium-term rat liver bioassay to detect tumor p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Matsushita, Kohei, Kijima, Aki, Ishii, Yuji, Takasu, Shinji, Jin, Meilan, Kuroda, Ken, Kawaguchi, Hiroaki, Miyoshi, Noriaki, Nohmi, Takehiko, Ogawa, Kumiko, Umemura, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society of Toxicologic Pathology 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620210/
https://ncbi.nlm.nih.gov/pubmed/23723564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.26.19
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados