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Inhibition of the Receptor Tyrosine Kinase ROR1 by Anti-ROR1 Monoclonal Antibodies and siRNA Induced Apoptosis of Melanoma Cells

The receptor tyrosine kinase (RTK) ROR1 is overexpressed and of importance for the survival of various malignancies, including lung adenocarcinoma, breast cancer and chronic lymphocytic leukemia (CLL). There is limited information however on ROR1 in melanoma. In the present study we analysed in seve...

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Hlavní autoři: Hojjat-Farsangi, Mohammad, Ghaemimanesh, Fatemeh, Daneshmanesh, Amir Hossein, Bayat, Ali-Ahmad, Mahmoudian, Jafar, Jeddi-Tehrani, Mahmood, Rabbani, Hodjatallah, Mellstedt, Hakan
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620154/
https://ncbi.nlm.nih.gov/pubmed/23593420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061167
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