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Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for Vibrio cholerae virulence

The function of the Vibrio 7(th) pandemic island-1 (VSP-1) in cholera pathogenesis has remained obscure. Utilizing ChIP-seq and RNA-seq to map the regulon of the master virulence regulator ToxT, we identify a TCP island encoded small RNA that reduces the expression of a previously unrecognized VSP-1...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Davies, Bryan W., Bogard, Ryan W., Young, Travis S., Mekalanos, John J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3620040/
https://ncbi.nlm.nih.gov/pubmed/22500802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.053
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