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Coordinated regulation of accessory genetic elements produces cyclic di-nucleotides for Vibrio cholerae virulence
The function of the Vibrio 7(th) pandemic island-1 (VSP-1) in cholera pathogenesis has remained obscure. Utilizing ChIP-seq and RNA-seq to map the regulon of the master virulence regulator ToxT, we identify a TCP island encoded small RNA that reduces the expression of a previously unrecognized VSP-1...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620040/ https://ncbi.nlm.nih.gov/pubmed/22500802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.01.053 |
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