Coordinated Changes in DNA Methylation in Antigen-Specific Memory CD4 T Cells

Memory CD4(+) T cells are central regulators of both humoral and cellular immune responses. T cell differentiation results in specific changes in chromatin structure and DNA methylation of cytokine genes. Although the methylation status of a limited number of gene loci in T cells has been examined,...

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Main Authors: Hashimoto, Shin-ichi, Ogoshi, Katsumi, Sasaki, Atsushi, Abe, Jun, Qu, Wei, Nakatani, Yoichiro, Ahsan, Budrul, Oshima, Kenshiro, Shand, Francis H. W., Ametani, Akio, Suzuki, Yutaka, Kaneko, Shuichi, Wada, Takashi, Hattori, Masahira, Sugano, Sumio, Morishita, Shinichi, Matsushima, Kouji
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Immunogenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619526/
https://ncbi.nlm.nih.gov/pubmed/23509353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202267
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