Unique mechanistic insights into the beneficial effects of soluble epoxide hydrolase inhibitors in the prevention of cardiac fibrosis

Tissue fibrosis represents one of the largest groups of diseases for which there are very few effective therapies. In the heart, myocardial infarction (MI) resulting in the loss of cardiac myocytes can culminate in adverse cardiac remodeling leading to eventual heart failure. Adverse cardiac remodel...

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Bibliographic Details
Main Authors: Sirish, Padmini, Li, Ning, Liu, Jun-Yan, Lee, Kin Sing Stephen, Hwang, Sung Hee, Qiu, Hong, Zhao, Cuifen, Ma, Siu Mei, López, Javier E., Hammock, Bruce D., Chiamvimonvat, Nipavan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2013
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619365/
https://ncbi.nlm.nih.gov/pubmed/23493561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221972110
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