Pheromone sensing regulates Caenorhabditis elegans lifespan and stress resistance via the deacetylase SIR-2.1

Lifespan in Caenorhabditis elegans, Drosophila, and mice is regulated by conserved signaling networks, including the insulin/insulin-like growth factor 1 (IGF-1) signaling cascade and pathways depending on sirtuins, a family of NAD(+)-dependent deacetylases. Small molecules such as resveratrol are o...

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Main Authors: Ludewig, Andreas H., Izrayelit, Yevgeniy, Park, Donha, Malik, Rabia U., Zimmermann, Anna, Mahanti, Parag, Fox, Bennett W., Bethke, Axel, Doering, Frank, Riddle, Donald L., Schroeder, Frank C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619363/
https://ncbi.nlm.nih.gov/pubmed/23509272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214467110
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