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Protein complex directs hemoglobin-to-hemozoin formation in Plasmodium falciparum

Malaria parasites use hemoglobin (Hb) as a major nutrient source in the intraerythrocytic stage, during which heme is converted to hemozoin (Hz). The formation of Hz is essential for parasite survival, but to date, the underlying mechanisms of Hb degradation and Hz formation are poorly understood. W...

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Detalhes bibliográficos
Main Authors: Chugh, Monika, Sundararaman, Vidhya, Kumar, Saravanan, Reddy, Vanga S., Siddiqui, Waseem A., Stuart, Kenneth D., Malhotra, Pawan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619337/
https://ncbi.nlm.nih.gov/pubmed/23471987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1218412110
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