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Oriented nucleation of hemozoin at the digestive vacuole membrane in Plasmodium falciparum
Heme detoxification is a critical step in the life cycle of malaria-causing parasites, achieved by crystallization into physiologically insoluble hemozoin. The mode of nucleation has profound implications for understanding the mechanism of action of antimalarial drugs that inhibit hemozoin growth. S...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3396484/ https://ncbi.nlm.nih.gov/pubmed/22745164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118120109 |
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