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Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response

Effective anticancer treatments often result in the induction of large amounts of tumour cell death. In vivo, such dying tumour cells are a potential source of antigens for T-cell stimulation. Although apoptosis is generally considered nonimmunogenic, recent evidence suggests that some anticancer th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Melis, M H M, Simpson, K L, Dovedi, S J, Welman, A, MacFarlane, M, Dive, C, Honeychurch, J, Illidge, T M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619244/
https://ncbi.nlm.nih.gov/pubmed/23412345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.8
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