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Unregulated expression of the erythropoietin receptor gene caused by insertion of spleen focus-forming virus long terminal repeat in a murine erythroleukemia cell line.

A murine erythroleukemia (MEL) cell line, F5-5, expressed 10,000 binding sites for erythropoietin (EPO) per cell, 10-fold more than was expressed by other murine erythroleukemia cell lines and normal erythroid progenitors. Northern (RNA) and Southern blot analyses revealed overexpression of mRNA for...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Hino, M, Tojo, A, Misawa, Y, Morii, H, Takaku, F, Shibuya, M
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361922/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1656233/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.11.5527
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