Unregulated expression of the erythropoietin receptor gene caused by insertion of spleen focus-forming virus long terminal repeat in a murine erythroleukemia cell line.

A murine erythroleukemia (MEL) cell line, F5-5, expressed 10,000 binding sites for erythropoietin (EPO) per cell, 10-fold more than was expressed by other murine erythroleukemia cell lines and normal erythroid progenitors. Northern (RNA) and Southern blot analyses revealed overexpression of mRNA for...

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Autores principales: Hino, M, Tojo, A, Misawa, Y, Morii, H, Takaku, F, Shibuya, M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1991
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC361922/
https://ncbi.nlm.nih.gov/pubmed/1656233
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