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LXR agonist modulation of cholesterol efflux in mice with intestine-specific deletion of microsomal triglyceride transfer protein

OBJECTIVE: Previous work demonstrated that intestinal cholesterol absorption and regulated expression of intestinal Npc1L1 and ABCA1 are all required for liver X agonist (LXR)-mediated increases in HDL biogenesis. We reexamined those conclusions in mice with intestine-specific deletion of the micros...

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Detalhes bibliográficos
Main Authors: Xie, Yan, Kennedy, Susan, Sidhu, Rohini, Luo, Jianyang, Ory, Daniel S., Davidson, Nicholas O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619218/
https://ncbi.nlm.nih.gov/pubmed/22580900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.246066
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