Propofol-Induced Protection of SH-SY5Y Cells against Hydrogen Peroxide Is Associated with the HO-1 via the ERK Pathway

Propofol (2, 6-diisopropylphenol), is an anesthetic and routinely used for the humans sedation during surgery. The potent inducers of phase II detoxifying and antioxidant stress responsive to propofol were investigated. First, a dose of 25-100 µM propofol showed no significant cytotoxicity on SH-SY5...

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Bibliographic Details
Main Authors: Gu, Jing, Chi, Meng, Sun, Xuechao, Wang, Guonian, Li, Mingming, Liu, Li, Li, Xuan
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2013
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619098/
https://ncbi.nlm.nih.gov/pubmed/23569422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.5151
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