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Icariside II Enhances Nrf2 Nuclear Translocation to Upregulate Phase II Detoxifying Enzyme Expression Coupled with the ERK, Akt and JNK Signaling Pathways

In the present study, the potent inducers of phase II detoxifying and antioxidant stress responsive to icariside II was investigated. First, a dose of 0–10 µM icariside II showed no significantly cytotoxicity on HepG2 cells by MTT assays and icariside II could enhance cellular GSH levels by ELISA as...

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Foilsithe in:Molecules
Main Authors: Gu, Jing, Sun, Xuechao, Wang, Guonian, Li, Mingming, Chi, Meng
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264540/
https://ncbi.nlm.nih.gov/pubmed/22051934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16119234
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