Alpha 2-macroglobulin restricts plasminogen activation to the surface of RC2A leukemia cells.

Human RC2A myelomonocytic leukemia cells are able to activate the prourokinase (pro-u-PA) they secrete so that active u-PA is present both in serum-free conditioned medium from these cells, as well as on the cell surface. When the cells are grown in serum-containing medium, no u-PA activity can be f...

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Pubblicato in:	Cell Regul
Autori principali:	Stephens, R W, Tapiovaara, H, Reisberg, T, Bizik, J, Vaheri, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Cell Biology 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1724917/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.2.12.1057
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