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Prourokinase activation on the surface of human rhabdomyosarcoma cells: localization and inactivation of newly formed urokinase-type plasminogen activator by recombinant class 2 plasminogen activator inhibitor.

Recombinant class 2 plasminogen activator inhibitor (PAI-2) was used in an approach to probe the formation and location of enzymatically active urokinase-type plasminogen activator (u-PA) sites on the surface of cultured human rhabdomyosarcoma cells (RD cells). Activation of pro-u-PA on the cell sur...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Pöllänen, J, Vaheri, A, Tapiovaara, H, Riley, E, Bertram, K, Woodrow, G, Stephens, R W
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2138329/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.6.2230
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