Effects of moderate-dose treatment with varenicline on neurobiological and cognitive biomarkers in smokers and nonsmokers with schizophrenia or schizoaffective disorder

CONTEXT: Nicotine administration transiently improves many neurobiological and cognitive functions in schizophrenia. It is not yet clear which nAChR subtype(s) is responsible for these seemingly pervasive nicotinic effects in schizophrenia. OBJECTIVE: α4β2 is a key nAChR subtype for nicotinic action...

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Hlavní autoři: Hong, L. Elliot, Thaker, Gunvant K., McMahon, Robert P., Summerfelt, Ann, RachBeisel, Jill, Fuller, Rebecca L., Wonodi, Ikwunga, Buchanan, Robert W., Myers, Carol, Heishman, Stephen J., Yang, Jeff, Nye, Adrienne
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618988/
https://ncbi.nlm.nih.gov/pubmed/21810630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archgenpsychiatry.2011.83
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