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Dipyridamole monotherapy in schizophrenia: Pilot of a novel treatment approach by modulation of purinergic signaling

BACKGROUND: Emerging data indicate the neuromodulator adenosine may play a role in the therapeutics of schizophrenia. Adenosine A(2A) receptor stimulation exerts a functional antagonism at postsynaptic D(2) receptors. Data from animal models relevant to schizophrenia support a therapeutic effect of...

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Hlavní autoři: Wonodi, Ikwunga, Gopinath, Hirekatur V., Liu, Judy, Adami, Htlene, Hong, L. Elliot, Allen-Emerson, Robert, McMahon, Robert P., Thaker, Gunvant K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009981/
https://ncbi.nlm.nih.gov/pubmed/21537940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2315-3
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