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Skin Basement Membrane: The Foundation of Epidermal Integrity—BM Functions and Diverse Roles of Bridging Molecules Nidogen and Perlecan

The epidermis functions in skin as first defense line or barrier against environmental impacts, resting on extracellular matrix (ECM) of the dermis underneath. Both compartments are connected by the basement membrane (BM), composed of a set of distinct glycoproteins and proteoglycans. Herein we are...

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Autors principals: Breitkreutz, Dirk, Koxholt, Isabell, Thiemann, Kathrin, Nischt, Roswitha
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618921/
https://ncbi.nlm.nih.gov/pubmed/23586018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/179784
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