Resurrecting ancestral alcohol dehydrogenases from yeast

Modern yeast living in fleshy fruits rapidly convert sugars into bulk ethanol through pyruvate. Pyruvate loses carbon dioxide to produce acetaldehyde, which is reduced by alcohol dehydrogenase 1 (Adh1) to ethanol, which accumulates. Yeast later consumes the accumulated ethanol, exploiting Adh2, an A...

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Bibliografiske detaljer
Main Authors: Thomson, J Michael, Gaucher, Eric A, Burgan, Michelle F, De Kee, Danny W, Li, Tang, Aris, John P, Benner, Steven A
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618678/
https://ncbi.nlm.nih.gov/pubmed/15864308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1553
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