Design and Characterization of a Novel Fluorinated Magnetic Resonance Imaging Agent for Functional Analysis of Bile Acid Transporter Activity

PURPOSE: Our objectives were to synthesize a trifluorinated bile acid that can be used for (19)F magnetic resonance imaging (MRI) of bile acid enterohepatic circulation, characterize its in vitro transporter affinity, stability, and (19)F-MRI signal, and assess its ability to concentrate in the gall...

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Bibliografiske detaljer
Main Authors: Vivian, Diana, Cheng, Kunrong, Khurana, Sandeep, Xu, Su, Whiterock, Valerie, Witter, Drew, Lentz, Kimberley A., Santone, Kenneth S., Raufman, Jean-Pierre, Polli, James E.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618595/
https://ncbi.nlm.nih.gov/pubmed/23319170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-012-0963-6
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