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SCF(Fbxl3) Ubiquitin Ligase Targets Cryptochromes at Their Cofactor Pocket
The flavoprotein cryptochromes (CRYs) act as blue-light receptors in plants and insects, but perform light-independent functions at the core of the mammalian circadian clock. To drive clock oscillations, mammalian CRYs associate with the Period proteins (PERs) and together inhibit the transcription...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618506/ https://ncbi.nlm.nih.gov/pubmed/23503662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11964 |
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