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Lubiprostone Decreases Mouse Colonic Inner Mucus Layer Thickness and Alters Intestinal Microbiota
BACKGROUND: Lubiprostone has been used to treat constipation through its effects to stimulate Cl(−) secretion, resulting in water and electrolyte secretion. AIM: Potential associated changes in intestinal mucus and the colonizing bacteria (microbiome) have not been studied. As mucus obstructions may...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618493/ https://ncbi.nlm.nih.gov/pubmed/23329012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10620-012-2509-5 |
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