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Quantitative Assessment of the Effect of Cytochrome P450 2C9 Gene Polymorphism and Colorectal Cancer

CYP2C9 enzyme activity is involved in the metabolism of substances related to colorectal cancer (CRC), and it is functionally linked to a genetic polymorphism. Two allelic variants of the CYP2C9 gene, namely CYP2C9*2 and CYP2C9*3, differ from wild-type CYP2C9*1 by single amino acid substitutions. Th...

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Bibliografske podrobnosti
Main Authors: Zhao, Yuan, Han, Yusong, Zhang, Liang, Wang, Yichao, Ma, Yushui, Zhang, Feng, Fu, Da, Wang, Xiaofeng
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618415/
https://ncbi.nlm.nih.gov/pubmed/23577132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060607
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