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Physical and Genetic Interactions Between Uls1 and the Slx5–Slx8 SUMO-Targeted Ubiquitin Ligase

The Slx5–Slx8 complex is a ubiquitin ligase that preferentially ubiquitylates SUMOylated substrates, targeting them for proteolysis. Mutations in SLX5, SLX8, and other SUMO pathway genes were previously identified in our laboratory as genomic suppressors of a point mutation (mot1-301) in the transcr...

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Autores principales: Tan, Wei, Wang, Zheng, Prelich, Gregory
Formato: Artigo
Lenguaje:Inglês
Publicado: Genetics Society of America 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618364/
https://ncbi.nlm.nih.gov/pubmed/23550137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.005827
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